Everolimus Impurity 43 CAS CATO-C4X-112243
| CAS No. | CATO-C4X-112243 |
| Molecular Formula | C55H87NO15 |
| Molecular Weight | 1002.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Everolimus Impurity 43.
Everolimus Impurity 43 (CAS CATO-C4X-112243) is a certified pharmaceutical impurity reference standard with the molecular formula C55H87NO15 and a molecular weight of 1002.28 g/mol.
Everolimus Impurity 43 (C55H87NO15) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C55H87NO15 |
| Molecular Weight | 1002.28 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus Impurity 35 (CAS CATO-C4X-112235)
- Everolimus Impurity 44 (CAS 159351-77-6)
- Everolimus Impurity 7 (CAS CATO-C4X-11227)
- Everolimus Impurity 32 (CAS CATO-C4X-112232)
- Everolimus Impurity 38 (CAS CATO-C4X-112238)
- Everolimus Impurity 40 (CAS CATO-C4X-112240)
- Everolimus Impurity 48 (CAS CATO-C4X-112248)
- Everolimus Impurity 37 (CAS 769905-89-7)
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