Ribociclib Impurity 19 CAS CATO-C4X-310019
| CAS No. | CATO-C4X-310019 |
| Molecular Formula | C24H27ClN6O2 |
| Molecular Weight | 466.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ribociclib Impurity 19 (CAS CATO-C4X-310019, C24H27ClN6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ribociclib Impurity 19 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ribociclib Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H27ClN6O2 |
| Molecular Weight | 466.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Ribociclib Standards
- Ribociclib Impurity 23 (CAS CATO-C4X-310023)
- Ribociclib Impurity 10 (CAS CATO-C4X-310010)
- Ribociclib impurity 2 (CAS CATO-C4X-31002)
- Ribociclib Impurity 9 (CAS 2460732-08-3)
- Ribociclib Impurity 25 (CAS CATO-C4X-310025)
- Ribociclib Impurity 21 (CAS CATO-C4X-310021)
- Ribociclib Impurity N1 (CAS 2069953-39-3)
- Ribociclib Impurity 17 (CAS 2514753-27-4)
Recommended Standards
- Tolvaptan Impurity 96 (CAS 1587638-01-4)
- Clobetasol Propionate EP Impurity C (CAS 25122-52-5)
- Brexpiprazole Impurity 74 (CAS CATO-C4X-113174)
- Clobetasol Propionate (CAS 25122-46-7)
- Donepezil Impurity 47 (CAS 36159-03-2)
- Vinpocetine Impurity 44 (CAS 68780-78-9)
- Rimegepant Impurity 121 (CAS CATO-C4X-2487121)
- 1-(Difluoromethoxy)-2-fluoronaphthalene (CAS 878998-79-9)
- N1-(2-Bromophenyl)ethane-1,2-diamine (CAS 748772-33-0)
- Ethyl 2-amino-4-methyl-5-(morpholine-4-carbonyl)thiophene-3-carboxylate (CAS 314046-67-8)
- Ethyl 1,3-dimethyl-4-phenylazepane-4-carboxylate (CAS 509-84-2)
- Ethyl 1-((3-((ethoxycarbonyl)oxy)phenyl)sulfonyl)cyclopropane-1-carboxylate (CAS 2169906-33-4)
- 2-Amino-5-hydroxy-hexanedioic acid diethyl ester hydrochloride (CAS 2097068-38-5)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com