Agomelatine Impurity 9 HCI CAS CATO-C4X-1132164
| CAS No. | CATO-C4X-1132164 |
| Molecular Formula | C26H26N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Agomelatine Impurity 9 HCI (C26H26N2O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 434.96 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Agomelatine Impurity 9 HCI (CAS CATO-C4X-1132164, C26H26N2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Agomelatine Impurity 9 HCI under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H26N2O2 HCl |
| Molecular Weight | 434.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Agomelatine Standards
- Agomelatine-D3 (CAS 107389-38-0)
- Agomelatine-d6 (CAS 1079389-42-6)
- Agomelatine-d4 (CAS 1079389-44-8)
- Agomelatine Impurity 33 (CAS 1079774-32-5)
- Agomelatine Hydrochloride (CAS 1176316-99-6)
- Agomelatine Impurity 36 (CAS 127299-26-7)
- Agomelatine Impurity 19 (CAS 1352139-51-5)
- Agomelatine Impurity 18 (CAS 1352303-07-1)
Recommended Standards
- Lotilaner Impurity 29 (CAS 2226274-70-8)
- Lotilaner Impurity 23 (CAS CATO-C4X-325623)
- Ramelteon Impurity 24 (CAS 221530-38-7)
- Methanaminium methoxydimethyl methyl sulfate (1:1) (CAS 21511-55-7)
- N-(3,4-difluorophenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide (CAS 306977-60-6)
- 1-(3,4-Dimethylphenyl)-5-phenyl-4,5-dihydro-1h-pyrazole-3-carboxylic acid (CAS 1264040-15-4)
- EThyl 2-isocyano-3-methylbutanoate (CAS 71014-99-8)
- 1-hexadecanoyl-2--(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate (sodium salt) 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphate (sodium salt) 16:0-20:4 PA 322647-60-9 PA(16:0/20:4(5Z,8Z,11Z,14Z)) PAPA (CAS 322647-60-9)
- 2,4-Dichloro-3,5-difluorophenylboronic acid (CAS 2377611-74-8)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com