Lotilaner Impurity 23 CAS CATO-C4X-325623
| CAS No. | CATO-C4X-325623 |
| Molecular Formula | C8H2Cl3F3O |
| Molecular Weight | 277.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lotilaner Impurity 23 (CAS CATO-C4X-325623, C8H2Cl3F3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lotilaner Impurity 23 (C8H2Cl3F3O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 277.46 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lotilaner Impurity 23 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H2Cl3F3O |
| Molecular Weight | 277.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Lotilaner Standards
- Lotilaner Impurity 20 (CAS CATO-C4X-325620)
- Lotilaner Impurity 4 (CAS CATO-C4X-32564)
- Lotilaner Impurity 21 (CAS CATO-C4X-325621)
- Lotilaner Impurity 29 (CAS 2226274-70-8)
- Lotilaner Impurity 7 (CAS CATO-C4X-32567)
- Lotilaner Impurity 24 (CAS CATO-C4X-325624)
- Lotilaner Impurity 22 (CAS CATO-C4X-325622)
- Lotilaner Impurity 15 (CAS CATO-C4X-325615)
Recommended Standards
- N,N-Diethyl-3-(triethoxysilyl)propan-1-amine (CAS 10049-42-0)
- 53012-82-1 2,6-Dichloro-3-(trifluoromethyl)benzoyl chloride MFCD11519345 (CAS 53012-82-1)
- 6-Bromo-2-chloro-8-fluoroquinazolin-4(3H)-one (CAS 1597156-83-6)
- 2,3-Dichloro-6-(trifluoromethyl)benzoyl chloride (CAS 886501-87-7)
- Loxoprofen Impurity 18 (CAS 99807-54-2)
- Perindopril Impurity 27 (CAS CATO-C4X-125227)
- Droperidol EP Impurity A (CAS 2147-83-3)
- Saxagliptin Impurity 79 (CAS CATO-C4X-104979)
- Zinc(II) (R,Z)-12-hydroxyoctadec-9-enoate (CAS 13040-19-2)
- Diethyl 5-nitro-2-oxo-6-phenyl-1,2-dihydropyridine-3,4-dicarboxylate (CAS 143323-42-6)
- tert-Butyl 8-benzyl-3,8-diazabicyclo[3.2.1]octane-3-carboxylate (CAS 201162-52-9)
- 2-((3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl)methyl)aniline (CAS 1469080-63-4)
- Ethyl ((1H-benzo[d][1,2,3]triazol-1-yl)methyl)carbamate (CAS 301168-87-6)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com