Olaparib Impurity 8 CAS CATO-C4X-11358
| CAS No. | CATO-C4X-11358 |
| Molecular Formula | C24H24N4O4 |
| Molecular Weight | 432.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Olaparib Impurity 8 (CAS CATO-C4X-11358), a pharmacopoeial impurity reference standard (molecular formula C24H24N4O4, MW 432.47 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Olaparib Impurity 8 (C24H24N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H24N4O4 |
| Molecular Weight | 432.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib (CAS 763113-22-0)
- Olaparib Impurity 122 (CAS CATO-C4X-1135122)
- Olaparib Impurity 123 (CAS CATO-C4X-1135123)
- Olaparib Impurity 124 (CAS CATO-C4X-1135124)
- Olaparib Impurity 125 (CAS CATO-C4X-1135125)
- Olaparib Impurity 126 (CAS CATO-C4X-1135126)
- Olaparib Impurity 127 (CAS CATO-C4X-1135127)
- Olaparib Impurity 116 (CAS CATO-C4X-1135116)
Recommended Standards
- Tetrakis(4-cyanophenyl)ethylene (CAS 79802-71-4)
- Tryptophan Impurity 52 (CAS CATO-C4X-137352)
- N-(3,4-Dimethylphenyl)-2-(4-((2-isonicotinoylhydrazono)methyl)-2-methoxyphenoxy)acetamide (CAS 332157-65-0)
- Nimodipine Impurity 47 (CAS CATO-C4X-138547)
- Fluticasone Impurity 48 (CAS 397864-58-3)
- Glycopyrronium Bromide Impurity 6 Iodide (CAS CATO-C4X-18176)
- Proparacaine Impurity 25 HCl (CAS 1081544-05-9)
- N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N3,N3-dimethylpropane-1,3-diamine (CAS 331956-10-6)
- 3-butylpiperazin-2-one (CAS 90152-25-3)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolidine hydrochloride (CAS 2642160-40-3)
- 2-(Dimethylamino)-N-hydroxy-N-methylacetamide (CAS 65753-93-7)
- 1-[2,4-Dichloro-5-(2-methoxyethoxy)phenyl]-2-(methylsulfanyl)-1H-imidazole (CAS 338967-19-4)
- (R)-2-Allylpyrrolidine hydrochloride (CAS 197230-31-2)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com