Abemaciclib Impurity 40 CAS CATO-C4X-293740

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-293740
Molecular FormulaC4H4ClFN2O
Molecular Weight150.54 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Abemaciclib Impurity 40 CAS CATO-C4X-293740 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 150.54 g/mol gives Abemaciclib Impurity 40 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Abemaciclib Impurity 40 (CAS CATO-C4X-293740), a pharmacopoeial impurity reference standard (molecular formula C4H4ClFN2O, MW 150.54 g/mol) used for the identification and quantification of trace impurities in APIs.

Abemaciclib Impurity 40 (C4H4ClFN2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Abemaciclib Impurity 40 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC4H4ClFN2O
Molecular Weight150.54 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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