Olaparib impurity 141 CAS CATO-C4X-1135141

Description

Compared with other compounds in its class, the molecular weight of 247.25 g/mol gives Olaparib impurity 141 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Olaparib impurity 141 (CAS CATO-C4X-1135141) is a certified pharmaceutical impurity reference standard with the molecular formula C16H9NO2 and a molecular weight of 247.25 g/mol.

The molecular framework of Olaparib impurity 141 (C16H9NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Olaparib impurity 141 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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