Olaparib Impurity 52 CAS CATO-C4X-113552
| CAS No. | CATO-C4X-113552 |
| Molecular Formula | C23H23FN4O4 |
| Molecular Weight | 438.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C23H23FN4O4, Olaparib Impurity 52 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 438.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Olaparib Impurity 52 (CAS CATO-C4X-113552, C23H23FN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H23FN4O4 |
| Molecular Weight | 438.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib-d5 (CAS 2143107-56-4)
- Olaparib Impurity 107 (CAS CATO-C4X-1135107)
- Olaparib Impurity 116 (CAS CATO-C4X-1135116)
- Olaparib Impurity 18 (CAS 2250243-17-3)
- Olaparib Impurity 70 (CAS CATO-C4X-113570)
- Olaparib (CAS 763113-22-0)
- Olaparib Impurity 122 (CAS CATO-C4X-1135122)
- Olaparib Impurity 123 (CAS CATO-C4X-1135123)
Recommended Standards
- 869884-78-6 53PC6LO35W Radezolid [USAN:INN] Acetamide, N-(((5S)-3-(2-fluoro-4'-(((1H-1,2,3-triazol-5-ylmethyl)amino)methyl)(1,1'-biphenyl)-4-yl)-2-oxo-5-oxazolidinyl)methyl)- Radezolid N-(((5S)-3-(2-Fluoro-4'-(((1H-1,2,3-triazol-5-ylmethyl)amino)methyl)biphenyl-4-yl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamide RX-01_667 RX-103 RX-1741 UNII-53PC6LO35W (CAS 869884-78-6)
- (3-Endo)-3-(Phenylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide (CAS 1170321-78-4)
- SIpOMeMesCuCl (CAS 2271064-72-1)
- tert-Butyl 2-(3,5-difluorophenyl)-4-(1-(methoxycarbonyl)cyclopentyl)-5-oxopiperazine-1-carboxylate (CAS 1415560-45-0)
- Norepinephrine impurity 149 (CAS CATO-C4X-1514149)
- Abiraterone Impurity 42 (CAS CATO-C4X-107042)
- Fluoropyrrolidine Impurity 3 (CAS CATO-C4X-31803)
- 1-[(4-bromophenyl)methyl]-1h-pyrazol-4-amine hydrochloride (CAS 1147233-82-6)
- 1-(7,7A-dihydro-1H-indol-1-yl)ethanone (CAS 41524-45-2)
- 2-Chloro-2,2-diphenylacetic acid (CAS 7475-56-1)
- {4-[(2,4-Dichlorobenzyl)oxy]phenyl}methanol (CAS 400825-70-9)
- Evocalcet impurity 59 (CAS CATO-C4X-248559)
- N-(3-bromopropyl)acetamide (CAS 51834-67-4)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
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