Olaparib Impurity 57 CAS CATO-C4X-113557
| CAS No. | CATO-C4X-113557 |
| Molecular Formula | C16H12FNO4 |
| Molecular Weight | 301.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Olaparib Impurity 57 (CAS CATO-C4X-113557), a pharmacopoeial impurity reference standard (molecular formula C16H12FNO4, MW 301.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Olaparib Impurity 57 (C16H12FNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 301.27 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12FNO4 |
| Molecular Weight | 301.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Olaparib Standards
- Olaparib Impurity 152 (CAS CATO-C4X-1135152)
- Olaparib Impurity 55 (CAS 2409514-28-7)
- Olaparib Impurity 1 (CAS 763114-26-7)
- Olaparib Impurity 159 (CAS CATO-C4X-1135159)
- Olaparib Impurity 97 (CAS CATO-C4X-113597)
- Olaparib Impurity 94 (CAS CATO-C4X-113594)
- Olaparib Impurity 2 (CAS 1956340-97-8)
- Olaparib Impurity 47 (CAS CATO-C4X-113547)
Recommended Standards
- 4,5,6,7-tetrahydro-1h-imidazo(4,5-c)pyridine-6-carboxylic acid 5021-45-4 AR-1F8239 (CAS 5021-45-4)
- Cyhalofop (CAS 122008-78-0)
- N-(6-acetylbenzo[d][1,3]dioxol-5-yl)-2-fluorobenzamide (CAS 666818-14-0)
- 2-(((5-Nitrothiazol-2-yl)amino)methylene)-1H-indene-1,3(2H)-dione (CAS 1023524-08-4)
- Levosimendan Impurity 31 (CAS 131741-05-4)
- Furosemide Impurity 26 (CAS CATO-C4X-140236)
- Tamsulosin Impurity 67 (CAS CATO-C4X-118767)
- 2-Amino-1-(2,5-dimethylthiophen-3-yl)ethan-1-ol (CAS 1304543-43-8)
- 1-(bromomethyl)-2-(difluoromethyl)naphthalene (CAS 1261843-74-6)
- (4-Chlorophenyl)[4-(3-piperidinylmethoxy)phenyl]-methanone (CAS 946724-86-3)
- 3-((tert-Butyldimethylsilyl)oxy)butan-2-one (CAS 108269-33-6)
- Methyl 3-(5-Bromo-4-fluoro-2-nitrophenyl)acrylate (CAS 2006281-56-5)
- 3-Methylhexahydro-1H-pyrrolo[1,2-c]imidazole (CAS 156171-66-3)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com