Olaparib Impurity 152 CAS CATO-C4X-1135152
| CAS No. | CATO-C4X-1135152 |
| Molecular Formula | C16H11FO5 |
| Molecular Weight | 302.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Olaparib Impurity 152.
Olaparib Impurity 152 (CAS CATO-C4X-1135152) is a certified pharmaceutical impurity reference standard with the molecular formula C16H11FO5 and a molecular weight of 302.25 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Olaparib Impurity 152 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Olaparib Impurity 152 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11FO5 |
| Molecular Weight | 302.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Olaparib Standards
- Olaparib Impurity 55 (CAS 2409514-28-7)
- Olaparib Impurity 57 (CAS CATO-C4X-113557)
- Olaparib Impurity 1 (CAS 763114-26-7)
- Olaparib Impurity 159 (CAS CATO-C4X-1135159)
- Olaparib Impurity 97 (CAS CATO-C4X-113597)
- Olaparib Impurity 94 (CAS CATO-C4X-113594)
- Olaparib Impurity 2 (CAS 1956340-97-8)
- Olaparib Impurity 47 (CAS CATO-C4X-113547)
Recommended Standards
- 927800-44-0 7-Bromo-4-(piperazin-1-yl)quinoline DTXSID10589210 (CAS 927800-44-0)
- 474707-24-9 6-bromanyl-4-piperazin-1-yl-quinoline 6-bromo-4-(1-piperazinyl)quinoline A827235 (CAS 474707-24-9)
- Ethyl 3-[1-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,2,4-oxadiazole-5-carboxylate (CAS 1242885-75-1)
- 6,7-Diethoxy-4-(trifluoromethyl)-2H-chromen-2-one (CAS 351002-66-9)
- Caffeine Impurity N5 (CAS 10184-35-7)
- Phytomenadione/Vitamin K1 Impurity 100 (CAS CATO-C4X-2207100)
- Nafamostat Impurity 58 (CAS CATO-C4X-133258)
- Telbivudine (CAS 3424-98-4)
- Letermovir Impurity 76 (CAS CATO-C4X-291576)
- 2-Amino-n-[3-(pyrrolidin-1-yl)phenyl]pentanamide (CAS 1218021-92-1)
- 3-ethylpentanal (CAS 39992-52-4)
- Methyl (2Z)-2-(benzenesulfonyl)-3-[(4-ethoxyphenyl)amino]prop-2-enoate (CAS 1327195-80-1)
- 5-Fluoro-N-(furan-3-ylmethyl)-2-methoxy-N-(2-methoxyethyl)benzenesulfonamide (CAS 1421512-45-9)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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