Lenvatinib Impurity 127 CAS CATO-C4X-1140127
| CAS No. | CATO-C4X-1140127 |
| Molecular Formula | C17H15N3O4 |
| Molecular Weight | 325.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lenvatinib Impurity 127 (C17H15N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Lenvatinib Impurity 127 (CAS CATO-C4X-1140127) is a certified pharmaceutical impurity reference standard with the molecular formula C17H15N3O4 and a molecular weight of 325.32 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lenvatinib Impurity 127 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15N3O4 |
| Molecular Weight | 325.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Lenvatinib Standards
- Lenvatinib Impurity 164 (CAS CATO-C4X-1140164)
- Lenvatinib Impurity 37 (CAS CATO-C4X-114037)
- Lenvatinib Impurity 96 (CAS CATO-C4X-114096)
- Lenvatinib Impurity N3 (CAS 205810-04-4)
- Lenvatinib Impurity 32 (CAS 205448-64-2)
- Lenvatinib Impurity 64 (CAS 2174956-62-6)
- Lenvatinib Impurity 14 (CAS CATO-C4X-114014)
- Lenvatinib Impurity 61 (CAS CATO-C4X-114061)
Recommended Standards
- Dronedarone Impurity 58 (CAS 141645-20-7)
- Nintedanib Impurity 175 (CAS CATO-C4X-1814175)
- Afatinib Impurity 76 (CAS CATO-C4X-100676)
- Cabozantinib Impurity 48 (CAS CATO-C4X-201848)
- Darunavir Impurity 17 (CAS 866594-61-8)
- Vonoprazan Impurity 254 DiHCl (CAS CATO-C4X-1020254)
- Lefamulinum Impurity 4 (CAS CATO-C4X-30474)
- 2-Chloro-7-propoxyquinazolin-4(1H)-one (CAS 62484-46-2)
- 2-[3-cyclopropyl-6-methyl-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937606-00-3)
- 3-(2-Chlorobenzyl)piperidin-3-ol (CAS 1342392-13-5)
- 2,4-dioxo-3-oxatricyclo[7.3.1.0⁵¹³]trideca-1(12),5,7,9(13),10-pentaene-8,10-dicarboxylic acid (CAS 52671-72-4)
- 4-Bromo-N-(1-(furan-2-yl)ethyl)aniline (CAS 1019576-57-8)
- 5-Bromo-6-fluoropyridine-3-sulfonyl chloride (CAS 1261801-69-7)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com