Cabozantinib Impurity 48 CAS CATO-C4X-201848

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-201848
Molecular FormulaC17H15N3O4
Molecular Weight325.32 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cabozantinib Impurity 48 CAS CATO-C4X-201848 chemical structure

Description

CATO supplies Cabozantinib Impurity 48 (CAS CATO-C4X-201848), a pharmacopoeial impurity reference standard (molecular formula C17H15N3O4, MW 325.32 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C17H15N3O4, Cabozantinib Impurity 48 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 325.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Cabozantinib Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC17H15N3O4
Molecular Weight325.32 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3

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