Sitagliptin Impurity 158 CAS CATO-C4X-1144158
| CAS No. | CATO-C4X-1144158 |
| Molecular Formula | C19H25F3N2O4 |
| Molecular Weight | 402.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Sitagliptin Impurity 158 (CAS CATO-C4X-1144158) is a certified pharmaceutical impurity reference standard with the molecular formula C19H25F3N2O4 and a molecular weight of 402.41 g/mol.
Sitagliptin Impurity 158 (C19H25F3N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sitagliptin Impurity 158 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H25F3N2O4 |
| Molecular Weight | 402.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Sitagliptin Standards
- Sitagliptin Impurity 85 (CAS CATO-C4X-114485)
- Sitagliptin Impurity 9 (CAS 767340-03-4)
- Sitagliptin Impurity 23 (CAS CATO-C4X-114423)
- Sitagliptin Impurity 24 (CAS CATO-C4X-114424)
- Sitagliptin Impurity 108 (CAS CATO-C4X-1144108)
- Sitagliptin Impurity 109 (CAS CATO-C4X-1144109)
- Sitagliptin Impurity 137 (CAS CATO-C4X-1144137)
- Sitagliptin Impurity 4 (CAS 764667-65-4)
Recommended Standards
- N-(2,4-difluorophenyl)-2-(N-phenylphenylsulfonamido)acetamide (CAS 339102-95-3)
- 9,9-Dimethyl-6-(4-(trifluoromethoxy)phenyl)-5,6,8,9,10,11-hexahydro-7H-dibenzo[b,e][1,4]diazepin-7-one (CAS 444151-02-4)
- Difloxacin-d3 (methyl-d3) (CAS 1173147-93-7)
- 4,4',4''-((1,3,5-Triazine-2,4,6-triyl)tris(oxy))trianiline (CAS 22065-34-5)
- Levosimendan Impurity 47 (CAS CATO-C4X-130847)
- 2,2'-((2-((2-aminoethyl)(carboxymethyl)amino)ethyl)azanediyl)diacetic acid (CAS 19156-82-2)
- Nerandomilast impurity 22 (CAS CATO-C4X-347322)
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- 1-[4-[[2,3-Dihydro-3-(phenylmethylene)-1H-cyclopenta[b]quinolin-9-yl]carbonyl]-1-piperazinyl]ethanone (CAS 1090542-32-7)
- (6-Bromo-5-cyclopropoxypyridin-2-yl)methanamine (CAS 1243360-09-9)
- 3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol (CAS 55828-88-1)
- Fmoc-2,3-difluoro-L-homophenylalanine (CAS 1260609-44-6)
- (2Z)-2-Amino-3-[(E)-[(3-phenoxyphenyl)methylidene]amino]but-2-enedinitrile (CAS 933949-57-6)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com