Sitagliptin Impurity 170 CAS CATO-C4X-1144170
| CAS No. | CATO-C4X-1144170 |
| Molecular Formula | C13H17F3N2O |
| Molecular Weight | 274.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sitagliptin Impurity 170 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Sitagliptin Impurity 170 (CAS CATO-C4X-1144170, C13H17F3N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Sitagliptin Impurity 170 (C13H17F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H17F3N2O |
| Molecular Weight | 274.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Sitagliptin Standards
- Sitagliptin Impurity 169 (CAS CATO-C4X-1144169)
- Sitagliptin Impurity 168 (CAS CATO-C4X-1144168)
- Sitagliptin Impurity 171 (CAS CATO-C4X-1144171)
- Sitagliptin Impurity 172 (CAS CATO-C4X-1144172)
- Sitagliptin Impurity 173 (CAS CATO-C4X-1144173)
- Sitagliptin Impurity 101 (CAS CATO-C4X-1144101)
- Sitagliptin Impurity 72 (CAS CATO-C4X-114472)
- Sitagliptin Impurity 60 (CAS CATO-C4X-114460)
Recommended Standards
- Fluvoxamine Impurity 15 (CAS 61718-83-0)
- 6-Amino-1-benzyl-5-(N-formyl-N-methyl)uracil 72816-89-8 N-[6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-N-methyl-formamide (CAS 72816-89-8)
- Olprinone Impurity 17 (CAS CATO-C4X-204317)
- 57075-57-7 6-amino-5-nitroso-2-(2-propoxyphenyl)-1H-pyrimidin-4-one 6-azanyl-5-nitroso-2-(2-propoxyphenyl)-1H-pyrimidin-4-one A831304 (CAS 57075-57-7)
- Dotinurad Impurity 152 (CAS CATO-C4X-2494152)
- Relebactam Impurity 29 (CAS CATO-C4X-214429)
- Rivaroxaban Impurity 78 (CAS CATO-C4X-109078)
- Potassium thiazol-2-ylprolinate (CAS 1231949-74-8)
- 4-(2,5-Dioxo-3-phenylpyrrolidin-1-yl)-3-methylbenzenesulfonamide (CAS 65116-56-5)
- (R)-2,2-dimethyl-1-(4-(trifluoromethoxy)phenyl)propan-1-amine (CAS 1390721-91-1)
- 2-Bromo-4-hydroxy-6-(trifluoromethyl)pyridine (CAS 1211535-77-1)
- 1-(3-Methyl-1,2,4-oxadiazol-5-yl)ethanamine (CAS 1041578-67-9)
- 2-((4-(Methylamino)pyrimidin-2-yl)amino)ethanol (CAS 476340-29-1)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com