Sitagliptin Impurity 101 CAS CATO-C4X-1144101
| CAS No. | CATO-C4X-1144101 |
| Molecular Formula | C12H16F3N3O |
| Molecular Weight | 275.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sitagliptin Impurity 101.
As a process- or degradation-related impurity, Sitagliptin Impurity 101 (CAS CATO-C4X-1144101, C12H16F3N3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Sitagliptin Impurity 101 (C12H16F3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sitagliptin Impurity 101 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16F3N3O |
| Molecular Weight | 275.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sitagliptin Standards
- Sitagliptin Impurity 173 (CAS CATO-C4X-1144173)
- Sitagliptin Impurity 72 (CAS CATO-C4X-114472)
- Sitagliptin Impurity 169 (CAS CATO-C4X-1144169)
- Sitagliptin Impurity 170 (CAS CATO-C4X-1144170)
- Sitagliptin Impurity 60 (CAS CATO-C4X-114460)
- Sitagliptin Impurity 168 (CAS CATO-C4X-1144168)
- Sitagliptin Impurity 171 (CAS CATO-C4X-1144171)
- Sitagliptin Impurity 172 (CAS CATO-C4X-1144172)
Recommended Standards
- 2738AE 3-{[4-(Trifluoromethoxy)phenoxy]methyl}piperidine 405090-60-0 C13H16F3NO2 (CAS 405090-60-0)
- 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl) phenyl] -, oxime (CAS 61747-22-6)
- 1-BROMO-3,5-DI-T-BUTYLBENZENE 1-Bromo-3,5-di-tert-butylbenzene 22385-77-9 3,5-DI-T-BUTYLBROMOBENZENE 3,5-DI-TERT-BUTYLBROMOBENZENE AS00267 ATTERCOP-CHM AT108639 TIMTEC-BB SBB005901 (CAS 22385-77-9)
- Fluvoxamine EP Impurity I (CAS 88699-84-7)
- Pregabalin Impurity 89 (CAS CATO-C4X-131289)
- Methocarbamol Impurity 10 (CAS 85536-84-1)
- Norepinephrine Impurity 65 (CAS CATO-C4X-151465)
- 4-chloro-2-methoxy-6-methylpyrimidine (CAS 97041-37-7)
- 4-(2-Chloro-4-fluorobenzyl)tetrahydro-2H-pyran-4-amine hydrochloride (CAS 1820650-70-1)
- 6-Chloro-2-propyl-3,4-dihydro-2h-1,4-benzoxazin-3-one (CAS 57463-12-4)
- 1-Phenylethane-1-sulfonyl fluoride (CAS 1936702-96-3)
- (S)-2-Amino-3-benzyloxy-1-propanol (HCl Salt) (CAS 61366-43-6)
- 3-(4-Methoxy-2-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 1171574-20-1)
- Neuropeptide Y (porcine) trifluoroacetate salt (CAS 83589-17-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com