N-Nitroso Diethyl Ester Methotrexate EP Impurity L CAS CATO-C4X-115458
| CAS No. | CATO-C4X-115458 |
| Molecular Formula | C17H23N3O6 |
| Molecular Weight | 365.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, N-Nitroso Diethyl Ester Methotrexate EP Impurity L is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 365.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, N-Nitroso Diethyl Ester Methotrexate EP Impurity L (CAS CATO-C4X-115458, C17H23N3O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures N-Nitroso Diethyl Ester Methotrexate EP Impurity L under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H23N3O6 |
| Molecular Weight | 365.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related N Standards
- N-Nitroso Vildagliptin Methyl Ester (CAS CATO-C4X-110086)
- N-Nitroso Hydroxychloroquine (CAS CATO-C4X-183563)
- N-Nitroso Ufenamate (CAS CATO-C4X-30691)
- N-Nitroso Linezolid Impurity 102 (CAS CATO-C4X-1073102)
- N-Nitroso Valaciclovir EP Impurity C (CAS CATO-C4X-124849)
- N-Nitroso Penicillenic Acid (CAS CATO-C4X-30961)
- N-Nitroso Izuforant (CAS CATO-C4X-30631)
- N-Nitroso Amoxicillin EP Impurity E (CAS CATO-C4X-114877)
Recommended Standards
- Methotrexate impurity 56 (CAS CATO-C4X-115456)
- Famciclovir Impurity 24 (CAS CATO-C4X-164224)
- Methotrexate impurity 54 (CAS CATO-C4X-115454)
- Nintedanib Impurity 24 (CAS CATO-C4X-181424)
- Coclaurine Impurity 112 (CAS 116331-72-7)
- Erythromycin EP Impurity C (CAS 41451-91-6)
- Indapamide EP Impurity B (CAS 63968-75-2)
- Methyl 4-allyl-3-hydroxy-2-methylbenzoate (CAS 1149388-00-0)
- Tetraethylene Glycol Dimethyl Ether (CAS 143-24-8)
- 2-(4-Ethylphenoxy)-2-methylpropanoic acid (CAS 17413-77-3)
- 4-(Tert-butyl)-N-(4-methylpiperazine-1-carbonothioyl)benzamide (CAS 497060-60-3)
- 4-Ethynyl-1,3,5-trimethyl-1h-pyrazole (CAS 22779-02-8)
- 5,5',5''-(((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tris(oxy))triisophthalic acid (CAS 1159974-70-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com