Sitafloxacin Isomer Impurity 8(RSS) HCl CAS CATO-C4X-115561
| CAS No. | CATO-C4X-115561 |
| Molecular Formula | C19H18ClF2N3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sitafloxacin Isomer Impurity 8(RSS) HCl is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Sitafloxacin Isomer Impurity 8(RSS) HCl (CAS CATO-C4X-115561), a pharmacopoeial impurity reference standard (molecular formula C19H18ClF2N3O3HCl, MW 446.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H18ClF2N3O3HCl, Sitafloxacin Isomer Impurity 8(RSS) HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 446.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Sitafloxacin Isomer Impurity 8(RSS) HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18ClF2N3O3 HCl |
| Molecular Weight | 446.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Sitafloxacin Standards
- Sitafloxacin Impurity 22 (CAS 101987-86-4)
- Sitafloxacin Impurity 25 (CAS 105919-35-5)
- Sitafloxacin impurity 90 (CAS 112062-51-8)
- Sitafloxacin Impurity 27 (CAS 119385-80-7)
- Sitafloxacin Impurity 17 (CAS 127199-00-2)
- Sitafloxacin Isomer Impurity 4(RSR) (CAS 127199-06-8)
- Sitafloxacin impurity 85 (CAS 127199-06-8（free base）)
- Sitafloxacin Impurity 23 (CAS 127199-15-9)
Recommended Standards
- (Z)-Ceftizoxime Impurity 19 (CAS CATO-C4X-179319)
- Cefoperazone Impurity 59 (CAS CATO-C4X-114959)
- Roxadustat Impurity 16 (CAS CATO-C4X-221316)
- (E)-6-(4-(Diphenylamino)styryl)-N,N-diphenylnaphthalen-2-amine (CAS 1093402-99-3)
- 6-Bromo-8-chloro-7-fluorocinnolin-3-amine (CAS 2581867-92-5)
- 1-(4-Methoxyphenyl)-3-(p-tolylthio)propan-1-one (CAS 20618-50-2)
- 5-(Aminomethyl)pyrimidin-2-amine dihydrochloride (CAS 672325-33-6)
- 7-Chloro-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one (CAS 1314912-26-9)
- 3′,4′,5′-Trifluoro[1,1′-biphenyl]-4-amine (CAS 1248629-22-2)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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