Dexamethasone impurity 66 CAS CATO-C4X-116566
| CAS No. | CATO-C4X-116566 |
| Molecular Formula | C24H33FO7 |
| Molecular Weight | 452.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dexamethasone impurity 66 (C24H33FO7) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Dexamethasone impurity 66 (CAS CATO-C4X-116566), a pharmacopoeial impurity reference standard (molecular formula C24H33FO7, MW 452.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dexamethasone impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H33FO7 |
| Molecular Weight | 452.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 129 (CAS CATO-C4X-1165129)
- Dexamethasone Impurity 115 (CAS CATO-C4X-1165115)
- Dexamethasone Impurity 86 (CAS 2796254-05-0)
- Dexamethasone 17-Propionate (CAS 15423-89-9)
- Dexamethasone 21-Propionate (CAS 3793-10-0)
- Dexamethasone Impurity 55 (CAS CATO-C4X-116555)
- Dexamethasone Impurity 83 (CAS 1879-87-4)
- Dexamethasone Acetate EP Impurity E (CAS 1524-94-3)
Recommended Standards
- Belumosudil (CAS 911417-87-3)
- Belumosudil Impurity 49 (CAS CATO-C4X-298849)
- Gsk2807 (CAS 2245255-65-4)
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- Vonoprazan Impurity 211 (CAS CATO-C4X-1020211)
- Lenvatinib Impurity 58 (CAS CATO-C4X-114058)
- Bilastine impurity 111 (CAS CATO-C4X-2253111)
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- (s)-5-(1-Amino-2-hydroxyethyl)-3-methoxybenzene-1,2-diol (CAS 1213932-12-7)
- 1-Methylpiperidin-3-yl 4-methylbenzenesulfonate (CAS 20177-94-0)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com