Dexamethasone Impurity 129 CAS CATO-C4X-1165129
| CAS No. | CATO-C4X-1165129 |
| Molecular Formula | C22H29O8P |
| Molecular Weight | 452.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 452.43 g/mol gives Dexamethasone Impurity 129 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Dexamethasone Impurity 129 (CAS CATO-C4X-1165129) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29O8P and a molecular weight of 452.43 g/mol.
Structurally, Dexamethasone Impurity 129 (C22H29O8P) contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.5, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 452.43 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H29O8P |
| Molecular Weight | 452.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Dexamethasone Standards
- Dexamethasone impurity 66 (CAS CATO-C4X-116566)
- Dexamethasone Impurity 115 (CAS CATO-C4X-1165115)
- Dexamethasone Impurity 86 (CAS 2796254-05-0)
- Dexamethasone 17-Propionate (CAS 15423-89-9)
- Dexamethasone 21-Propionate (CAS 3793-10-0)
- Dexamethasone Impurity 55 (CAS CATO-C4X-116555)
- Dexamethasone Impurity 83 (CAS 1879-87-4)
- Dexamethasone Acetate EP Impurity E (CAS 1524-94-3)
Recommended Standards
- 6-Acetyl-3-amino-N-(4-fluorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 727664-47-3)
- Betamethasone Impurity 111 (CAS CATO-C4X-1437111)
- 3,4-Bis(4-methoxyphenyl)-1-[3-(trifluoromethyl)benzoyl]-1H-pyrazole (CAS 956356-50-6)
- Betamethasone Impurity 143 (CAS CATO-C4X-1437143)
- Ulipristal Impurity 19 (CAS CATO-C4X-191519)
- Hydrocortisone Impurity 27 Acetate (CAS 7753-60-8（free base）)
- Perospirone Impurity 10 (CAS CATO-C4X-245810)
- Isopanose (CAS 32581-33-2)
- 3-Bromo-5-chloro-N-methylpyridin-4-amine (CAS 1335051-94-9)
- 8-[(E)-2-[(2,3-Dichlorophenyl)methylidene]hydrazin-1-yl]quinoline (CAS 478258-68-3)
- Dexamethasone Sodium Phosphate EP Impurity F (CAS CATO-C4X-116530)
- 3-Methyl-3-hepten-5-one (CAS 1447-26-3)
- n-(1-Methoxybutan-2-yl)cyclohexanamine (CAS 1339365-39-7)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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