Rosuvastatin EP Impurity B(Calcium Salt) CAS CATO-C4X-11692
| CAS No. | CATO-C4X-11692 |
| Molecular Formula | 2*C22H27FN3O6S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rosuvastatin EP Impurity B(Calcium Salt) is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Rosuvastatin EP Impurity B(Calcium Salt) (CAS CATO-C4X-11692, C22H27FN3O6SCa) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rosuvastatin EP Impurity B(Calcium Salt) (C22H27FN3O6SCa) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.5, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 520.61 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rosuvastatin EP Impurity B(Calcium Salt) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C22H27FN3O6S Ca |
| Molecular Weight | 520.61 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 205 (CAS 1007871-85-3)
- Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) (CAS 1024064-70-7)
- Rosuvastatin Impurity 267 (CAS 1031246-43-1)
- Rosuvastatin Impurity 19 (CAS 1035595-71-1)
- Rosuvastatin Impurity 27 (CAS 1044518-75-3)
- Rosuvastatin Impurity 192 (CAS 1092844-00-2)
- Rosuvastatin Impurity 123 (CAS 1112048-62-0)
- Rosuvastatin Impurity 37 (CAS 1197348-98-3)
Recommended Standards
- Tofacitinib Impurity 235 (CAS CATO-C4X-1079235)
- Vildagliptin Impurity 60 (CAS 1211679-98-9)
- Flurbiprofen Impurity 82 (CAS 37847-52-2)
- Lacosamide Impurity 17 (CAS CATO-C4X-183017)
- 2-Methyl-2-azaspiro[3.3]heptan-6-amine (CAS 2081079-38-9)
- 3-Methylnonan-3-ol (CAS 21078-72-8)
- Osimertinib Impurity 89 (CAS CATO-C4X-204589)
- 2,2,2-Trifluoroethyl (2-(furan-2-yl)-2-(pyrrolidin-1-yl)ethyl)carbamate (CAS 1210912-39-2)
- 5-(3-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid (CAS 483315-67-9)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com