Salbutamol Impurity 140 CAS CATO-C4X-1176140
| CAS No. | CATO-C4X-1176140 |
| Molecular Formula | C17H29NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 409.44 g/mol gives Salbutamol Impurity 140 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Salbutamol Impurity 140 (CAS CATO-C4X-1176140, C17H29NO3C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Salbutamol Impurity 140 (C17H29NO3C2HF3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H29NO3 C2HF3O2 |
| Molecular Weight | 409.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 130 (CAS 115061-55-7)
- Salbutamol Impurity 134 (CAS 115787-50-3)
- Salbutamol Impurity 55 (CAS 115787-52-5)
- Salbutamol Impurity 85 (CAS 115787-52-5（free base）)
- Salbutamol Impurity 87 (CAS 115787-53-6)
- Salbutamol-d3 (CAS 1219798-60-3)
- Salbutamol Impurity 75 (CAS 1221726-71-1)
- Salbutamol Impurity 146 (CAS 124658-76-0)
Recommended Standards
- Relugolix Impurity 78 (CAS CATO-C4X-242978)
- (R)-Norepinephrine Impurity 77 (CAS 77469-51-3)
- Carbetocin Impurity 26 (CAS CATO-C4X-191126)
- 3-Chloro-6-methoxy-1H-indole-2-carboxylic acid (CAS 1355231-20-7)
- Chromium trifluoride tetrahydrate (CAS 123333-98-2)
- Bis(2-chlorophenyl)methanol (CAS 6335-15-5)
- Bis-PEG6-t-butyl ester (CAS 439114-12-2)
- 1-((Difluoromethyl)sulfonyl)-4-nitrobenzene (CAS 24906-74-9)
- 5-(3,4-Dihydro-2H-pyrrol-5-yl)-N,N,4-trimethylpyridin-2-amine (CAS 1352523-47-7)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com