Salbutamol Impurity 185 CAS CATO-C4X-1176185
| CAS No. | CATO-C4X-1176185 |
| Molecular Formula | C13H12Br2O5 |
| Molecular Weight | 408.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Salbutamol Impurity 185.
Salbutamol Impurity 185 (CAS CATO-C4X-1176185) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12Br2O5 and a molecular weight of 408.04 g/mol.
The molecular framework of Salbutamol Impurity 185 (C13H12Br2O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12Br2O5 |
| Molecular Weight | 408.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ＞95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Salbutamol Standards
- Salbutamol Impurity 184 (CAS CATO-C4X-1176184)
- Salbutamol Impurity 78 (CAS CATO-C4X-117678)
- Salbutamol Impurity P (CAS CATO-C4X-1176161)
- Salbutamol Impurity 222 (CAS CATO-C4X-1176222)
- Salbutamol Impurity N19 (CAS 77430-27-4)
- Salbutamol Impurity 173 (CAS CATO-C4X-1176173)
- Salbutamol Impurity 180 (CAS CATO-C4X-1176180)
- Salbutamol Impurity 195 (CAS CATO-C4X-1176195)
Recommended Standards
- 5-Bromo-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-β]pyridine (CAS 1416713-91-1)
- 6,7-Dimethoxy-1H-indole (CAS 31165-13-6)
- 6-Bromo-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine (CAS 1416712-53-2)
- (E)-4-((3,5-dibromo-2,4-dihydroxybenzylidene)amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 468755-27-3)
- Econazole Impurity 4 (CAS 137958-96-4)
- N-Nitroso Risperidone Impurity 48 (CAS CATO-C4X-111148)
- Rivaroxaban Impurity 49 (CAS 148857-42-5)
- Methyl 3-fluoro-5-[3-(2-methoxy-2-oxoethyl)phenyl]benzoate (CAS 1820640-49-0)
- N-(5-chloro-2-fluoro-4-iodo-phenyl)acetamide (CAS 2157481-37-1)
- Olaparib Impurity 103 (CAS 2691818-05-8)
- 3-Methyl-1-(4-nitrophenyl)piperazine (CAS 329922-44-3)
- (1-(4-Fluorophenyl)pyrrolidin-3-yl)methanol hydrochloride (CAS 1017456-32-4)
- 1-(tert-Butyl) 4-methyl 3-iodo-1H-indazole-1,4-dicarboxylate (CAS 944899-19-8)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
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