Salbutamol Impurity 222 CAS CATO-C4X-1176222
| CAS No. | CATO-C4X-1176222 |
| Molecular Formula | C22H31NO6 |
| Molecular Weight | 405.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 405.48 g/mol gives Salbutamol Impurity 222 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Salbutamol Impurity 222 (CAS CATO-C4X-1176222, C22H31NO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Salbutamol Impurity 222 (C22H31NO6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H31NO6 |
| Molecular Weight | 405.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity P (CAS CATO-C4X-1176161)
- Salbutamol Impurity 173 (CAS CATO-C4X-1176173)
- Salbutamol Impurity 180 (CAS CATO-C4X-1176180)
- Salbutamol Impurity 184 (CAS CATO-C4X-1176184)
- Salbutamol Impurity 185 (CAS CATO-C4X-1176185)
- Salbutamol Impurity 78 (CAS CATO-C4X-117678)
- Salbutamol Impurity 125 (CAS CATO-C4X-1176125)
- Salbutamol Impurity N19 (CAS 77430-27-4)
Recommended Standards
- (S)-2-(tert-Butoxy)-2-(4-(chroman-6-yl)-2-methylquinolin-3-yl)acetic acid (CAS 1155270-57-7)
- 2-[5,6-Dimethoxy-1'-[(2-methylpropan-2-yl)oxycarbonyl]spiro[1,2-dihydroindene-3,4'-piperidine]-1-yl]acetic acid (CAS 1160247-56-2)
- PF-05175157 (CAS 1301214-47-0)
- Orforglipron impurity 131 (CAS CATO-C4X-3234131)
- Phenylephrine Impurity 23 (CAS CATO-C4X-146723)
- Atorvastatin Impurity 166 (CAS CATO-C4X-1132166)
- Levofloxacin Impurity 88 (CAS CATO-C4X-137188)
- (3,5-Dimethyl-2,4,6-trioxo-1,3,5-triazinan-1-yl)acetonitrile (CAS 893770-15-5)
- Salcaprozate Impurity 6 (CAS CATO-C4X-25076)
- 4,4-Difluoro-1-oxaspiro[4.5]decan-8-one (CAS 2770344-59-5)
- 6-Chloro-5-cyclopropylmethoxypyridine-2-carbaldehyde (CAS 1288989-08-1)
- (E)-3-(2,3-difluorophenyl)acrylaldehyde (CAS 1254840-98-6)
- 1-(1-Phenylcyclobutanecarbonyl)piperidine-4-carboxylic acid (CAS 1099048-69-7)
- Renin Inhibitor Peptide (CAS 50410-01-0)
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