Salbutamol EP Impurity A(Trifluoroacetic Acid) CAS CATO-C4X-117649
| CAS No. | CATO-C4X-117649 |
| Molecular Formula | C14H23NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.36 g/mol gives Salbutamol EP Impurity A(Trifluoroacetic Acid) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Salbutamol EP Impurity A(Trifluoroacetic Acid) (CAS CATO-C4X-117649, C14H23NO3C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Salbutamol EP Impurity A(Trifluoroacetic Acid) (C14H23NO3C2HF3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H23NO3 C2HF3O2 |
| Molecular Weight | 367.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 130 (CAS 115061-55-7)
- Salbutamol Impurity 134 (CAS 115787-50-3)
- Salbutamol Impurity 55 (CAS 115787-52-5)
- Salbutamol Impurity 85 (CAS 115787-52-5（free base）)
- Salbutamol Impurity 87 (CAS 115787-53-6)
- Salbutamol-d3 (CAS 1219798-60-3)
- Salbutamol Impurity 75 (CAS 1221726-71-1)
- Salbutamol Impurity 146 (CAS 124658-76-0)
Recommended Standards
- Pinaverium Bromide Impurity 19 (CAS CATO-C4X-246719)
- Neratinib Impurity 1 (CAS CATO-C4X-11341)
- Sofosbuvir Impurity 98 (CAS CATO-C4X-105298)
- Methyl 6-phenyl-5-(p-tolyl)picolinate (CAS 1011301-80-6)
- Methyl 5-methyl-2,4-dioxohexanoate (CAS 20577-64-4)
- 3-bromo-5-(bromomethyl)pyridine hydrobromide (CAS 173999-33-2)
- 2-Bromo-1-(bromomethyl)-3,4-dimethoxybenzene (CAS 147912-63-8)
- 2-(4-(2-Hydroxyethyl)piperazin-1-yl)nicotinonitrile (CAS 1017782-85-2)
- 2-(Benzofuran-2-yl)-5-(pyridin-2-yl)-1,3,4-oxadiazole (CAS 1081113-46-3)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com