Chlorphenamine EP Impurity A (DiHCl) CAS CATO-C4X-11885
| CAS No. | CATO-C4X-11885 |
| Molecular Formula | C16H24ClN3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Chlorphenamine EP Impurity A (DiHCl) is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Chlorphenamine EP Impurity A (DiHCl) (CAS CATO-C4X-11885, C16H24ClN3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Chlorphenamine EP Impurity A (DiHCl) (C16H24ClN3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Chlorphenamine EP Impurity A (DiHCl) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H24ClN3 2*HCl |
| Molecular Weight | 330.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorphenamine Standards
- Chlorphenamine Impurity 60 (CAS 1081516-68-8)
- Chlorphenamine EP Impurity B (CAS 1202-34-2)
- Chlorphenamine Impurity 8 (CAS 120244-82-8（free base）)
- Chlorphenamine Impurity 25 (CAS 122376-68-5)
- Chlorphenamine impurity 58 (CAS 123517-65-7)
- Chlorphenamine EP Impurity A (CAS 1246816-57-8)
- Chlorphenamine Impurity 61Maleic Acid (CAS 19428-44-5（free base）)
- Chlorphenamine Impurity 6 (CAS 20101-92-2)
Recommended Standards
- Atrasentan Impurity 180 (CAS 1059052-58-2)
- Urapidil Impurity 36 (CAS 5770-44-5)
- Cefcapene Impurity 45 (CAS CATO-C4X-182445)
- 2-(Isoquinolin-7-yloxy)acetic acid (CAS 86235-60-1)
- 1-Bromo-3-(tert-butyl)-5-iodobenzene (CAS 186772-43-0)
- 2-(2,2-Dicyclohexylethyl)piperidine (CAS 39648-48-1)
- 1-(2-fluoroethyl)pyrrolidin-3-ol (CAS 1556837-13-8)
- 4-Bromo-5-acetamidoindanone (CAS 429682-68-8)
- ethyl 3-(butylamino)-3-sulfanylidenepropanoate (CAS 57005-83-1)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com