Quetiapine Impurity 61 CAS 65141-02-8
| CAS No. | 65141-02-8 |
| Molecular Formula | C13H10ClNO2 |
| Molecular Weight | 247.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Quetiapine Impurity 61.
As a process- or degradation-related impurity, Quetiapine Impurity 61 (CAS 65141-02-8, C13H10ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Quetiapine Impurity 61 (C13H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Quetiapine Impurity 61 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClNO2 |
| Molecular Weight | 247.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Quetiapine Standards
- Quetiapine Impurity 58 (CAS CATO-C4X-124458)
- Quetiapine Impurity 32 (CAS 13745-86-3)
- Quetiapine Impurity 55 (CAS 54920-98-8)
- Quetiapine Impurity N2 (CAS 20290-48-6)
- Quetiapine impurity 83 (CAS 2101854-40-2)
- Quetiapine Impurity SF (CAS 22871-33-6)
- Quetiapine impurity 71 (CAS 1798293-04-5)
- Quetiapine Impurity 89 (CAS CATO-C4X-124489)
Recommended Standards
- Chlorphenamine impurity 52 (CAS CATO-C4X-118852)
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- Ulipristal Impurity 13 (CAS CATO-C4X-191513)
- Olaparib Impurity 70 (CAS CATO-C4X-113570)
- Rivaroxaban Impurity 171 (CAS CATO-C4X-1090171)
- Alogliptin Impurity 63 (CAS 147754-12-9)
- 2-Bromo-4-chloro-5-(trifluoromethyl)pyridine (CAS 1211587-96-0)
- Everolimus Impurity 16 (CAS 147438-29-7)
- 5,6-Dichloro-3-methylpyrimidin-4(3H)-one (CAS 55609-71-7)
- 4-Bromo-N-(2,6-difluorophenyl)benzenesulfonamide (CAS 701933-54-2)
- 5-(5-Tert-butyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1,3,4-oxadiazole-2-thiol (CAS 885460-60-6)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com