Captopril Impurity 27 CAS CATO-C4X-119027
| CAS No. | CATO-C4X-119027 |
| Molecular Formula | C18H23NO5S |
| Molecular Weight | 365.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Captopril Impurity 27 (C18H23NO5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Captopril Impurity 27 (CAS CATO-C4X-119027, C18H23NO5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23NO5S |
| Molecular Weight | 365.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Captopril Standards
- Captopril EP Impurity H (CAS 205521-07-9)
- Captopril Impurity 34 (CAS CATO-C4X-119034)
- Captopril Impurity 30 (CAS CATO-C4X-119030)
- Captopril Impurity 33 (CAS 75479-46-8)
- Captopril EP Impurity M (CAS 83326-98-1)
- Captopril Impurity 28 (CAS CATO-C4X-119028)
- Captopril Impurity 42 (CAS CATO-C4X-119042)
- Captopril Impurity 29 (CAS CATO-C4X-119029)
Recommended Standards
- Edoxaban Impurity 75 (CAS 1255529-31-7)
- Camphor Impurity 9 (CAS CATO-C4X-21149)
- N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)methanesulfonamide (CAS 897622-15-0)
- Edoxaban Impurity N5 (CAS 365997-36-0)
- Dipivefrine EP Impurity A (CAS 329-65-7)
- Bortezomib Impurity 28 (CAS 205393-22-2)
- Evocalcet Impurity 47 (CAS CATO-C4X-248547)
- Epinephrine Impurity 21 (CAS 16899-83-5)
- 1-(2-Amino-3-methylphenyl)propan-1-one (CAS 62819-85-6)
- 4-Oxo-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid (CAS 1539750-84-9)
- 4-Phenylpentan-1-ol (CAS 19967-24-9)
- 3-Fluoro-5-(pentafluoro-λ6-sulfanyl)benzamide (CAS 1240256-88-5)
- 2-Hydroxyethyl (E)-2-(2-hydroxy-3-methoxybenzylidene)hydrazine-1-carboxylate (CAS 339016-13-6)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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