Bortezomib Impurity 28 CAS 205393-22-2
| CAS No. | 205393-22-2 |
| Molecular Formula | C29H39BN4O4 |
| Molecular Weight | 518.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Bortezomib Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Bortezomib Impurity 28 (CAS 205393-22-2) is a certified pharmaceutical impurity reference standard with the molecular formula C29H39BN4O4 and a molecular weight of 518.46 g/mol.
Bortezomib Impurity 28 (C29H39BN4O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C29H39BN4O4 |
| Molecular Weight | 518.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Nitrogen Atoms | 4 |
Related Bortezomib Standards
- Bortezomib Impurity 55 (CAS 1375004-39-9)
- Bortezomib Impurity 62 (CAS CATO-C4X-107262)
- Bortezomib D-Mannitol Ester (CAS 444576-08-3)
- Bortezomib Impurity 18 (CAS CATO-C4X-107218)
- Bortezomib Impurity 26 (CAS CATO-C4X-107226)
- Bortezomib Impurity 27 Sodium Salt (CAS 16480-57-2)
- Bortezomib Impurity 51 (CAS 1194235-14-7)
- Bortezomib Impurity N47 (CAS 514820-48-5)
Recommended Standards
- Methyl 3,6-Di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside (CAS 68601-74-1)
- CiceritolDISCONTINUED (CAS 88167-26-4)
- ((2R,3S,4S,5R,6R)-6-(((2R,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl 3-(4-hydroxy-3-methoxyphenyl)acrylate (CAS 118230-77-6)
- 3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444156-88-1)
- Bumetanide Impurity 53 (CAS CATO-C4X-198653)
- Hydrocortisone Impurity 31 (CAS 10184-70-0)
- Posaconazole Impurity 201 (CAS CATO-C4X-1208201)
- (3aS,6aS)-5-Boc-1H-hexahydropyrrolo[3,4-b]pyrrole (CAS 370882-55-6)
- (S)-3-Benzyl-1-methyl-piperazine dihydrochloride (CAS 1965305-43-4)
- 3-(1,2,3,4-Tetrahydro-9H-carbazol-9-yl)propanenitrile (CAS 24115-51-3)
- 2-(Chloromethyl)-4,5-dimethoxy-3-methylpyridine hydrochloride (CAS 102625-85-4)
- [D-Pen2, Pen5] Enkephalin (CAS 88373-72-2)
- Methyl 4-(imino(methoxy)methyl)benzoate (CAS 63617-57-2)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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