Eltrombopag Impurity 10 CAS CATO-C4X-119810
| CAS No. | CATO-C4X-119810 |
| Molecular Formula | C13H8N2O3 |
| Molecular Weight | 240.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Eltrombopag Impurity 10 (C13H8N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Eltrombopag Impurity 10 (CAS CATO-C4X-119810, C13H8N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Eltrombopag Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8N2O3 |
| Molecular Weight | 240.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Eltrombopag Standards
- Eltrombopag Impurity 49 (CAS 67666-03-9)
- Eltrombopag Impurity 50 (CAS 29418-36-8)
- Eltrombopag Impurity 42 (CAS 612-87-3)
- Eltrombopag Impurity 52 (CAS CATO-C4X-119852)
- Eltrombopag Impurity 157 (CAS CATO-C4X-1198157)
- Eltrombopag Impurity 94 (CAS 1176777-76-6)
- Eltrombopag Impurity 95 (CAS 2230800-88-9)
- Eltrombopag Impurity 26 (CAS CATO-C4X-119826)
Recommended Standards
- Gefitinib Impurity 86 (CAS CATO-C4X-111786)
- Disalicylide (CAS 486-58-8)
- Sofosbuvir Impurity 106 (CAS 119410-95-6)
- Cinitapride impurity 9 (CAS 86718-17-4)
- Isavuconazole Impurity 100 Iodization HCl (CAS CATO-C4X-1236100)
- Peridine Impurity 2 (CAS 143900-43-0)
- Relebactam Impurity 71 (CAS CATO-C4X-214471)
- 11-Methyl-9,10-dihydro-9,10-ethanoanthracene (CAS 32363-36-3)
- 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinolin-7-amine (CAS 859826-71-4)
- (2-Oxabicyclo[3.1.1]heptan-1-yl)methanol (CAS 2225146-47-2)
- 2-Bromo-3,6-difluorobenzenethiol (CAS 1349715-83-8)
- Dasatinib Impurity 11 (CAS 87-63-8)
- (Octahydro-1H-4,7-methanoinden-5-yl)methanol (CAS 57526-50-8)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com