Dasatinib Impurity 11 CAS 87-63-8
| CAS No. | 87-63-8 |
| Molecular Formula | C7H8ClN |
| Molecular Weight | 141.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dasatinib Impurity 11 is closely related to a nitrile group, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dasatinib Impurity 11 (CAS 87-63-8) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8ClN and a molecular weight of 141.60 g/mol.
Based on its molecular formula C7H8ClN, Dasatinib Impurity 11 contains a nitrile group, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 141.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dasatinib Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8ClN |
| Molecular Weight | 141.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dasatinib Standards
Recommended Standards
- 4-Chloro-3-methylaniline (CAS 7149-75-9)
- 4-Chloro-2-methylaniline (CAS 95-69-2)
- 2-Chloro-3-methylaniline (CAS 29027-17-6)
- 2-Chloro-4-Methylaniline (CAS 615-65-6)
- Duloxetine Impurity 57 HCI (CAS 494221-37-3;763079-11-4（free base）)
- Ezetimibe Impurity 51 (CAS 693-13-0)
- Lacosamide EP Impurity H(RR-Isomer) (CAS CATO-C4X-18301)
- 1,3-Diethyl 2-[6-chloro-4-(trifluoromethyl)pyridin-2-yl]-2-ethylpropanedioate (CAS 882747-55-9)
- 161119-98-8 5153AD C13H15NO N-(2-Furylmethyl)-1-phenyl-1-ethanamine (CAS 161119-98-8)
- 5-(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)quinoline (CAS 1354951-32-8)
- 4-Methyl-N-(2-(5-neopentyl-1H-1,2,4-triazol-3-yl)ethyl)aniline (CAS 1279203-98-3)
- (S)-2-Amino-3-(6-phenylpyridin-3-yl)propanoic acid (CAS 1335566-07-8)
- 4-Fluorocatechol (CAS 367-32-8)
- Semaglutide238 (CAS CATO-C4X-2226238)
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