Eltrombopag Impurity 42 CAS 612-87-3

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.612-87-3
Molecular FormulaC14H10O4
Molecular Weight242.23 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Eltrombopag Impurity 42 CAS 612-87-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 242.23 g/mol gives Eltrombopag Impurity 42 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Eltrombopag Impurity 42 (CAS 612-87-3) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10O4 and a molecular weight of 242.23 g/mol.

Eltrombopag Impurity 42 (C14H10O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Eltrombopag Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC14H10O4
Molecular Weight242.23 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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