Eltrombopag Impurity 128 CAS CATO-C4X-1198128
| CAS No. | CATO-C4X-1198128 |
| Molecular Formula | C20H17NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Eltrombopag Impurity 128 (CAS CATO-C4X-1198128), a pharmacopoeial impurity reference standard (molecular formula C20H17NO3C2HF3O2, MW 433.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Eltrombopag Impurity 128 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 433.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Eltrombopag Impurity 128 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H17NO3 C2HF3O2 |
| Molecular Weight | 433.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 39 (CAS 103966-66-1)
- Eltrombopag Impurity 89 (CAS 1097777-60-0)
- Eltrombopag Impurity 94 (CAS 1176777-76-6)
- Eltrombopag Impurity 102 (CAS 118048-94-5)
- Eltrombopag-13C4 (CAS 1217230-31-3)
- Eltrombopag Methyl Ester (CAS 1246929-01-0)
- Eltrombopag Impurity 4 (CAS 1246929-02-1)
- Eltrombopag Impurity 34 (CAS 13073-25-1)
Recommended Standards
- Upadacitinib Impurity 171 (CAS CATO-C4X-2405171)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
- Dimemorfan Phosphate Impurity 5 (CAS CATO-C4X-33585)
- (OC-6-12)-[1,1'-Bis(diphenylphosphino-κP)ferrocene]dichloro(1,2-ethanediamine-κN1,κN2)ruthenium (CAS 853412-10-9)
- Ethyl 6,6''-dimethyl-[2,2':6',2''-terpyridine]-4'-carboxylate (CAS 372520-84-8)
- 1-Cyclohexylidenepropan-2-one (CAS 874-68-0)
- 4-Chloro-6-cyclobutoxypyrimidine (CAS 1247342-59-1)
- 3-Methoxy-5-(trifluoromethyl)benzamide (CAS 916420-94-5)
- 2-((4-Aminothieno[2,3-d]pyrimidin-2-yl)thio)-N-cyclopropylacetamide (CAS 923707-56-6)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com