Eltrombopag Impurity 138 CAS CATO-C4X-1198138
| CAS No. | CATO-C4X-1198138 |
| Molecular Formula | C15H15NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Eltrombopag Impurity 138 (CAS CATO-C4X-1198138), a pharmacopoeial impurity reference standard (molecular formula C15H15NO3HCl, MW 293.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H15NO3HCl, Eltrombopag Impurity 138 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 293.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H15NO3 HCl |
| Molecular Weight | 293.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 39 (CAS 103966-66-1)
- Eltrombopag Impurity 89 (CAS 1097777-60-0)
- Eltrombopag Impurity 94 (CAS 1176777-76-6)
- Eltrombopag Impurity 102 (CAS 118048-94-5)
- Eltrombopag-13C4 (CAS 1217230-31-3)
- Eltrombopag Methyl Ester (CAS 1246929-01-0)
- Eltrombopag Impurity 4 (CAS 1246929-02-1)
- Eltrombopag Impurity 34 (CAS 13073-25-1)
Recommended Standards
- Upadacitinib Impurity 192 HCl (CAS CATO-C4X-2405192)
- Pheniramine Maleate （Dexchlorpheniramine EP Impurity A Maleate Salt） (CAS 132-20-7)
- CAS CATO-C4X-32404 (CAS CATO-C4X-32404)
- RWJ-67657 (CAS 215303-72-3)
- 6-Methoxyharman (CAS 3589-72-8)
- 1-(5-Fluoro-2-methylphenyl)cyclopropan-1-ol (CAS 1342212-34-3)
- Meldonium impurity B CRS (CAS 34810-18-9)
- 3-(((Benzyloxy)carbonyl)amino)benzoic acid (CAS 34240-09-0)
- 3-Amino-2-(pyridin-4-ylmethyl)propan-1-ol (CAS 1017209-70-9)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com