Posaconazole impurity 217 CAS CATO-C4X-1208217

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1208217
Molecular FormulaC22H21F2NO4
Molecular Weight401.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Posaconazole impurity 217 CAS CATO-C4X-1208217 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 401.40 g/mol gives Posaconazole impurity 217 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Posaconazole impurity 217 (CAS CATO-C4X-1208217) is a certified pharmaceutical impurity reference standard with the molecular formula C22H21F2NO4 and a molecular weight of 401.40 g/mol.

Based on its molecular formula C22H21F2NO4, Posaconazole impurity 217 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 401.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Posaconazole impurity 217 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H21F2NO4
Molecular Weight401.40 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms1

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