Posaconazole Impurity 204 CAS CATO-C4X-1208204
| CAS No. | CATO-C4X-1208204 |
| Molecular Formula | C14H14F2IN3O |
| Molecular Weight | 405.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Posaconazole Impurity 204 (CAS CATO-C4X-1208204, C14H14F2IN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Posaconazole Impurity 204 (C14H14F2IN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 405.18 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Posaconazole Impurity 204 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14F2IN3O |
| Molecular Weight | 405.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ＞95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 3 |
Related Posaconazole Standards
- Posaconazole Impurity 129 (CAS 74853-06-8)
- Posaconazole Impurity 121 (CAS 212632-01-4)
- Posaconazole impurity 217 (CAS CATO-C4X-1208217)
- Posaconazole Impurity 203 (CAS CATO-C4X-1208203)
- Posaconazole Impurity 257 (CAS CATO-C4X-1208257)
- Posaconazole impurity 229 (CAS CATO-C4X-1208229)
- Posaconazole Impurity 44 (CAS 357189-97-0)
- Posaconazole Impurity 253 (CAS CATO-C4X-1208254)
Recommended Standards
- 3-Cyano-6-(2,4-dichlorophenyl)pyridin-2-yl 2,6-difluorobenzoate (CAS 400075-80-1)
- Dimethyl (4-iodobenzoyl)glutamate (CAS 473444-31-4)
- (4-Bromophenyl)dimesitylborane (CAS 38186-40-2)
- Methyl (2Z)-3-[(3-chloro-2-methylphenyl)amino]-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]prop-2-enoate (CAS 1164550-03-1)
- Trifarotene impurity 14 (CAS CATO-C4X-313214)
- Dotinurad Impurity 10 (CAS 1285573-42-3)
- Cladribine Impurity N78 (CAS 152463-98-4)
- Itraconazole-D9 (CAS 1309272-50-1)
- ((2-Fluoro-6-(methoxymethoxy)-8-vinylnaphthalen-1-yl)ethynyl)triisopropylsilane (CAS 2812580-45-1)
- 4-Phthalimidoacetoacetic Acid Ethyl Ester-13C (CAS 123253-99-6)
- 2-(5-(5,6,7,8-Tetrahydronaphthalen-2-yl)isoxazol-3-yl)acetic acid (CAS 1018663-18-7)
- 3-Methoxy-3-oxopropane-1-sulfinic acid (CAS 71561-98-3)
- Glipizide EP Impurity A (CAS 33288-71-0)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com