Posaconazole Impurity 8 CAS CATO-C4X-12088
| CAS No. | CATO-C4X-12088 |
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Posaconazole Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Posaconazole Impurity 8 (CAS CATO-C4X-12088, C13H20N2O2C2H2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H20N2O2C2H2O4, Posaconazole Impurity 8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 326.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H20N2O2 C2H2O4 |
| Molecular Weight | 326.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Posaconazole Standards
- Posaconazole Impurity 25 (CAS 1042398-26-4)
- Posaconazole Impurity 112 (CAS 110931-77-6)
- Posaconazole Impurity 111 (CAS 112559-81-6)
- Posaconazole-d4 (CAS 1133712-26-1)
- Posaconazole Impurity 84 (CAS 122151-32-0)
- Posaconazole Impurity 115 (CAS 122151-38-6)
- Posaconazole Impurity 67(R,S,R,R) (CAS 1229428-89-0)
- Posaconazole Impurity 22(R,S,S,R) (CAS 1229428-90-3)
Recommended Standards
- Avanafil Impurity 113 (CAS CATO-C4X-1118113)
- Vericiguat impurity 53 (CAS CATO-C4X-289653)
- Febuxostat Impurity 84 (CAS 2428631-65-4)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-hydroxyethyl)-N-methylpiperidine-4-carboxamide (CAS 303150-26-7)
- {6,7-Dimethoxy-2-[(4-methoxyphenyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-1-yl}acetic acid (CAS 932539-69-0)
- (4-chloro-3-pyridyl)methanol (CAS 189449-41-0)
- Methyl 2-amino-3-(4-chloro-1h-pyrazol-1-yl)propanoate (CAS 1249897-59-3)
- tert-Butyl 2-(2-hydroxyphenyl)acetate (CAS 258331-10-1)
- Methyl 5-amino-2-methylthiophene-3-carboxylate (CAS 1239942-97-2)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
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