Vericiguat impurity 53 CAS CATO-C4X-289653
| CAS No. | CATO-C4X-289653 |
| Molecular Formula | C19H16F2N8O |
| Molecular Weight | 410.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vericiguat impurity 53.
CATO supplies Vericiguat impurity 53 (CAS CATO-C4X-289653), a pharmacopoeial impurity reference standard (molecular formula C19H16F2N8O, MW 410.38 g/mol) used for the identification and quantification of trace impurities in APIs.
Vericiguat impurity 53 (C19H16F2N8O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vericiguat impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F2N8O |
| Molecular Weight | 410.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Vericiguat Standards
- Vericiguat Impurity 62 (CAS CATO-C4X-289662)
- Vericiguat Impurity 100 (CAS 1011527-86-8)
- Vericiguat Impurity 3 (CAS 3052969-91-9)
- Vericiguat impurity 47 (CAS CATO-C4X-289647)
- Vericiguat Impurity 77 (CAS CATO-C4X-289677)
- Vericiguat Impurity 17 (CAS 625115-49-3)
- Vericiguat Impurity 67 (CAS 2755814-39-0)
- Vericiguat (CAS 1350653-20-1)
Recommended Standards
- Roxadustat Impurity 28 (CAS CATO-C4X-221328)
- Podophyllotoxin Impurity N2 (CAS 42123-27-3)
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Why CATO?
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