Ceftazidime Oxide Impurity 1 CAS CATO-C4X-121211
| CAS No. | CATO-C4X-121211 |
| Molecular Formula | C22H22N6O8S2 |
| Molecular Weight | 562.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Ceftazidime Oxide Impurity 1 (CAS CATO-C4X-121211, C22H22N6O8S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ceftazidime Oxide Impurity 1 (C22H22N6O8S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C22H22N6O8S2 |
| Molecular Weight | 562.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Ceftazidime Standards
- Ceftazidime Oxide Impurity 2 (CAS CATO-C4X-121212)
- Ceftazidime Impurity 19 (CAS CATO-C4X-121219)
- Ceftazidime Impurity 29 (CAS CATO-C4X-121229)
- Ceftazidime EP Impurity H (CAS 1354396-23-8)
- Ceftazidime Impurity 109 (CAS CATO-C4X-1212109)
- Ceftazidime Impurity 44 (CAS 2259869-88-8)
- Ceftazidime-d5 (CAS CATO-CCAD303625)
- [2H6]-Ceftazidime sodium salt (CAS CATO-C4X-121239)
Recommended Standards
- 3-[[(8α,9S)-6'-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione (CAS 1256245-85-8)
- 3-[[(9R)-6'-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione (CAS 1256245-80-3)
- Suc-Ala-Ala-Pro-Abu-pNA (CAS 108392-27-4)
- Iopromide Impurity 30 (CAS CATO-C4X-183230)
- Neratinib Impurity 29 (CAS CATO-C4X-113429)
- Montelukast EP Impurity G (CAS 774538-96-4)
- Budesonide Impurity 22(Mixture of Diastereomers) (CAS CATO-C4X-138922)
- 6-Methyl-2-propylimidazo[2,1-b][1,3,4]thiadiazole-5-carboxylic acid (CAS 1181305-66-7)
- 5-Bromo-2-methyl-1-(phenylsulfonyl)-4-azaindole (CAS 1448259-50-4)
- 3-Chloro-7-nitroquinoxalin-2-amine (CAS 251537-40-3)
- Glucosamine sulfate impurity 23 (CAS 1136-44-3)
- (Trichloromethoxy)benzene (CAS 34888-05-6)
- N-Benzyl-1-(4-ethoxyphenyl)methanamine 333755-96-7 (CAS 333755-96-7)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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