Ceftazidime impurity 115 CAS CATO-C4X-1212115
| CAS No. | CATO-C4X-1212115 |
| Molecular Formula | C47H54ClN12O18S4 |
| Molecular Weight | 1238.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ceftazidime impurity 115 (C47H54ClN12O18S4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ceftazidime impurity 115 (CAS CATO-C4X-1212115) is a certified pharmaceutical impurity reference standard with the molecular formula C47H54ClN12O18S4 and a molecular weight of 1238.71 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ceftazidime impurity 115 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C47H54ClN12O18S4 |
| Molecular Weight | 1238.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 26.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 12 |
| Sulfur Atoms | 4 |
Related Ceftazidime Standards
- Ceftazidime impurity 122 (CAS CATO-C4X-1212122)
- Ceftazidime dimer 1 (CAS CATO-C4X-121264)
- Ceftazidime dimer 6 (CAS CATO-C4X-121266)
- Ceftazidime dimer 2 (CAS CATO-C4X-121265)
- Ceftazidime Impurity 21 (CAS CATO-C4X-121221)
- Ceftazidime Impurity 54 (CAS CATO-C4X-121254)
- Ceftazidime Impurity 22 (CAS CATO-C4X-121222)
- Ceftazidime Impurity 94 (CAS CATO-C4X-121294)
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- Buserelin EP Impurity A (CAS CATO-C4X-22121)
- Edoxaban Impurity 116 (CAS 2089454-69-1)
- Paracetamol EP Impurity B (CAS 1693-37-4)
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