Isavuconazole Impurity 101 CAS CATO-C4X-1236101
| CAS No. | CATO-C4X-1236101 |
| Molecular Formula | C49H52F2N11O11S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isavuconazole Impurity 101.
CATO supplies Isavuconazole Impurity 101 (CAS CATO-C4X-1236101), a pharmacopoeial impurity reference standard (molecular formula C49H52F2N11O11SI, MW 1167.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, Isavuconazole Impurity 101 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 1167.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C49H52F2N11O11S I |
| Molecular Weight | 1167.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 11 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Brivaracetam Impurity 166 (CAS 2755924-55-9)
- Meclizine Impurity N2 (CAS 713071-37-5)
- Etoricoxib Impurity 2 (CAS 316149-01-6)
- (3,3-Diethoxypropyl)diethylamine (CAS 3616-60-2)
- 2-(Dimethylamino)-2-(m-tolyl)acetic acid hydrochloride (CAS 1390653-98-1)
- 7-Chloro-8-hydroxyquinoline-5-sulfonic acid (CAS 3062-36-0)
- 2-(3-Chlorobenzenesulfonamido)propanoic acid (CAS 1008997-34-9)
- 4-Hydroxy-5,5-dimethylhexan-2-one (CAS 101713-95-5)
- 4-Bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (CAS 2413775-05-8)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com