Isavuconazole Impurity 11 CAS CATO-C4X-123611
| CAS No. | CATO-C4X-123611 |
| Molecular Formula | C54H60F2N11O13S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Isavuconazole Impurity 11 (CAS CATO-C4X-123611), a pharmacopoeial impurity reference standard (molecular formula C54H60F2N11O13SC21H46NI, MW 1580.70 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Isavuconazole Impurity 11 (C54H60F2N11O13SC21H46NI) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C54H60F2N11O13S C21H46N I |
| Molecular Weight | 1580.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 27.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 12 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Bupropion Impurity 54 (CAS CATO-C4X-120354)
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- N-[2-(3-Methyl-1,2,4-oxadiazol-5-yl)ethyl]methanesulfonamide (CAS 1312132-81-2)
- 6-Methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 4931-24-2)
- Methyl 2-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 1559157-90-2)
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- 2-Chloro-4-nitropyrimidin-5-amine (CAS 618397-67-4)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com