Isavuconazole Impurity 186 CAS CATO-C4X-1236186
| CAS No. | CATO-C4X-1236186 |
| Molecular Formula | C42H43F2N10O5S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isavuconazole Impurity 186.
CATO supplies Isavuconazole Impurity 186 (CAS CATO-C4X-1236186), a pharmacopoeial impurity reference standard (molecular formula C42H43F2N10O5SIHCl, MW 1001.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Isavuconazole Impurity 186 (C42H43F2N10O5SIHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 24.0, corresponding to approximately 24 ring(s) or double-bond equivalent(s). With a molecular weight of 1001.28 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Isavuconazole Impurity 186 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C42H43F2N10O5S I HCl |
| Molecular Weight | 1001.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 10 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Cefotaxime Impurity 38 (CAS CATO-C4X-120138)
- Ergometrine Maleate EP Impurity H (CAS 29477-88-1)
- Ketorolac Impurity 34 (CAS CATO-C4X-166934)
- Fluconazole EP Impurity H (R-Isomer) (CAS CATO-C4X-101966)
- N-(7-Amino-1,3-dioxoisoindolin-4-yl)acetamide (CAS 24469-08-7)
- 2-Butyl-2-(hydroxymethyl)hexanenitrile (CAS 83576-49-2)
- 3-(3-Methoxypyridin-2-yl)propanoic acid (CAS 139745-96-3)
- (S)-(+)-2-(Methoxymethyl)pyrrolidine (CAS 63126-47-6)
- 2-Methyl-1-(1-methyl-1h-pyrazol-4-yl)propan-2-ol (CAS 1249173-82-7)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com