Efinaconazole impurity 51 CAS CATO-C4X-124351
| CAS No. | CATO-C4X-124351 |
| Molecular Formula | C18H22FN4O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Efinaconazole impurity 51 (CAS CATO-C4X-124351), a pharmacopoeial impurity reference standard (molecular formula C18H22FN4OBr, MW 409.30 g/mol) used for the identification and quantification of trace impurities in APIs.
Efinaconazole impurity 51 (C18H22FN4OBr) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Efinaconazole impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22FN4O Br |
| Molecular Weight | 409.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 4 |
Related Efinaconazole Standards
- Efinaconazole Impurity G (CAS 109105-86-4)
- Efinaconazole Impurity 9 (CAS 1175536-50-1)
- Efinaconazole Impurity 30 (CAS 124627-86-7)
- Efinaconazole Impurity 14 (CAS 126918-16-9)
- Efinaconazole Impurity 35 (CAS 127001-03-0)
- Efinaconazole (2S,3R) epoxide, 98% (CAS 132563-77-0)
- Efinaconazole Impurity 12 (CAS 133775-25-4)
- Efinaconazole Impurity 2 (CAS 135133-23-2)
Recommended Standards
- Furosemide Impurity 49 (CAS CATO-C4X-140249)
- CAS CATO-C3D-262483 (CAS CATO-C3D-262483)
- Vilanterol Impurity 70 (CAS CATO-C4X-193570)
- 1-(1-Methylpiperidin-3-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 651024-39-4)
- N-methoxy-N-methyl-2-(3,4,5-trifluorophenyl)cyclopropane-1-carboxamide (CAS 1803609-46-2)
- 2-(2-Bromophenyl)-5,5-diethylmorpholine (CAS 1281533-33-2)
- 3-Chloro-5-(2,5-dimethoxyphenyl)-1,2,4-triazine (CAS 1368788-86-6)
- 2-Formylnicotinic acid (CAS 23590-67-2)
- 6-Amino-[3,3'-bipyridine]-5-carbaldehyde (CAS 1227599-09-8)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com