Furosemide Impurity 49 CAS CATO-C4X-140249
| CAS No. | CATO-C4X-140249 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Furosemide Impurity 49 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Furosemide Impurity 49 (CAS CATO-C4X-140249), a pharmacopoeial impurity reference standard (molecular formula C10H9NO2, MW 175.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Furosemide Impurity 49 (C10H9NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Furosemide Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Furosemide Standards
- Furosemide Impurity 33 (CAS 1803102-41-1)
- Furosemide Impurity 57 (CAS 19377-82-3)
- Furosemide Impurity 32 (CAS 18240-50-1)
- Furosemide Impurity 57 (CAS 5428-37-5)
- Furosemide EP Impurity E (CAS 50-84-0)
- Furosemide Impurity 41 (CAS 137-65-5)
- Furosemide Impurity 34 (CAS 6660-65-7)
- Furosemide Impurity 21 (CAS 30170-04-8)
Recommended Standards
- Famotidine impurity 75 (CAS 90924-16-6)
- Metronidazole-d4 (CAS 1261392-47-5)
- Isavuconazole Impurity 72 (CAS 192225-36-8)
- Ketoprofen Impurity 37 (CAS 18908-59-3)
- Prilocaine Impurity 63 (CAS CATO-C4X-193463)
- Ibrutinib Impurity 186 (CAS CATO-C4X-1064186)
- Midazolam Impurity 31 (CAS CATO-C4X-150931)
- 4-Fluorophenyl isocyanide (CAS 24075-34-1)
- Enzalutamide Impurity 8 (CAS CATO-C4X-10168)
- 3-Nitrobiphenyl-4-amine (CAS 4085-18-1)
- 2S-t-Butyldimethylsilyloxy-3R-(t-Boc)-amino-1,4-dichlorobutane 326480-00-6 [(1R,2S)-3-Chloro-1-(chloromethyl)-2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]carbamic Acid 1,1-Dimethylethyl Ester (CAS 326480-00-6)
- Ethyl 4-methoxy-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxylate (CAS 478262-61-2)
- 5-(Isopropyl(methyl)amino)pentanoic acid (CAS 1037159-98-0)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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