Efinaconazole Impurity 12 CAS 133775-25-4
| CAS No. | 133775-25-4 |
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C12H13F2N3O2, Efinaconazole Impurity 12 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 269.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Efinaconazole Impurity 12 (CAS 133775-25-4) is a certified pharmaceutical impurity reference standard with the molecular formula C12H13F2N3O2 and a molecular weight of 269.25 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Efinaconazole Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Efinaconazole Standards
- Efinaconazole Impurity 3 (CAS 135272-36-5)
- Efinaconazole Impurity 37 (CAS CATO-C4X-124337)
- Efinaconazole Impurity 4 (CAS 135270-05-2)
- Efinaconazole Impurity 5 (CAS 135270-11-0)
- Efinaconazole Impurity 7 (CAS CATO-C4X-12437)
- Efinaconazole Impurity 9 (CAS CATO-C4X-12439)
- Efinaconazole Impurity 35 (CAS 127001-03-0)
- Efinaconazole Impurity 27 (CAS 136081-74-8)
Recommended Standards
- Isavuconazole impurity 70 (CAS CATO-C4X-1236170)
- Isavuconazole impurity 69 (CAS CATO-C4X-1236169)
- Isavuconazole impurity 68 (CAS CATO-C4X-1236168)
- Propargyl-PEG2-NHS ester (CAS 2512228-06-5)
- Cyclophosphamide Impurity 15 (CAS CATO-C4X-230615)
- Cefpodoxime Proxetil EP Impurity A (CAS 80210-62-4)
- Tofacitinib Impurity 230 (CAS CATO-C4X-1079230)
- 6,7-Dimethoxy-4-(pentylamino)quinazoline-2(1H)-thione (CAS 901868-37-9)
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- 4-[4-(Ethoxycarbonyl)benzenesulfonamido]butanoic acid (CAS 743451-77-6)
- (R)-TERT-BUTYL 4-BENZYL-2-METHYLPIPERAZINE-1-CARBOXYLATE (CAS 170033-58-6)
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- 2-(5-Bromo-3-(trifluoromethyl)-1H-pyrazol-4-yl)propan-2-ol (CAS 2159078-26-7)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com