Quetiapine EP Impurity I Fumarate CAS CATO-C4X-124453
| CAS No. | CATO-C4X-124453 |
| Molecular Formula | C19H21N3OS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Quetiapine EP Impurity I Fumarate (CAS CATO-C4X-124453) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21N3OSC4H4O4 and a molecular weight of 455.53 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Quetiapine EP Impurity I Fumarate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 455.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21N3OS C4H4O4 |
| Molecular Weight | 455.53 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine Carboxylate Impurity (CAS 1011758-00-1)
- Quetiapine EP Impurity P (CAS 1011758-03-4)
- Quetiapine EP Impurity P Hemifumarate (CAS 1011758-03-4（free base）)
- Quetiapine Impurity 56 (CAS 1015-89-0)
- Quetiapine Impurity N3 (CAS 102893-57-2)
- Quetiapine-d8 HemifumarateDISCONTINUED. Please see Q510002. (CAS 1031703-36-2)
- Quetiapine EP Impurity H (CAS 1076199-40-0)
- Quetiapine (CAS 111974-69-7)
Recommended Standards
- Furosemide Impurity 15 (CAS CATO-C4X-140215)
- Vortioxetine Impurity 50 (CAS CATO-C4X-105650)
- Lovastatin Impurity 44 (CAS CATO-C4X-168444)
- PF 184 (CAS 1187460-81-6)
- Ethyl 1-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine-4-carboxylate (CAS 1268692-87-0)
- 1-Chloro-3-methylbut-3-en-2-one (CAS 193958-16-6)
- 4-bromo-3-cyanobenzene-1-sulfonamide (CAS 1261670-91-0)
- Ethyl (4-methyl-4H-pyrrolo[3,2-d]thiazol-2-yl)carbamate (CAS 72083-53-5)
- 6-Iodopravadoline (CAS 164178-33-0)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com