Erdafitinib Impurity 2 CAS 123342-12-1
| CAS No. | 123342-12-1 |
| Molecular Formula | C8H4Br2N2O |
| Molecular Weight | 303.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Erdafitinib Impurity 2 (CAS 123342-12-1), a pharmacopoeial impurity reference standard (molecular formula C8H4Br2N2O, MW 303.94 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H4Br2N2O, Erdafitinib Impurity 2 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 303.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Erdafitinib Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4Br2N2O |
| Molecular Weight | 303.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Erdafitinib Standards
- Erdafitinib Impurity 12 (CAS CATO-C4X-261612)
- Erdafitinib Impurity 3 (CAS 380639-03-2)
- Erdafitinib Impurity 4 (CAS 2731009-66-6)
- Erdafitinib Impurity 10 (CAS 2839751-66-3)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
- Erdafitinib Impurity 14 (CAS CATO-C4X-261614)
- Erdafitinib Impurity 1 (CAS 40534-39-2)
Recommended Standards
- 2,4-Dibromo-3,5-difluorobenzenethiol (CAS 1208077-53-5)
- 5,7-Dibromoquinazolin-4(3H)-one (CAS 860192-99-0)
- 2,5-Dibromo-3,6-difluorothiophenol (CAS 1263376-36-8)
- 4,6-Dibromophthalazin-1(2H)-one (CAS 2750149-30-3)
- Ezetimibe Impurity 71 (CAS CATO-C4X-109871)
- N-Nitroso Resmetirom impurity 140 (CAS CATO-C4X-2912140)
- Finerenone Impurity 266 (CAS CATO-C4X-2880266)
- 4-ethylfuran-2-carboxylic acid (CAS 1515682-02-6)
- Dimetilan (CAS 644-64-4)
- 544-13-8 01ZI68F3CQ Glutaronitrile Pentanedinitrile 1,3-Trimethylenedinitrile 4-02-00-01941 (Beilstein Handbook Reference) AI3-07024 BRN 1738385 1,3-Dicyanopropane EINECS 208-861-6 Glutaric acid dinitrile Glutarodinitrile NSC 3807 Pyrotartaric acid nitrile UNII-01ZI68F3CQ (CAS 544-13-8)
- Ethyl 7-oxododecanoate (CAS 58262-36-5)
- 3-Amino-5-trifluoromethyl-pyridine hydrochloride (CAS 1414958-36-3)
- Metopimazine-d6 (CAS 1215315-86-8)
- HIV (gp120) Antigenic Peptide (H-2982.0500) (CAS 198636-94-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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