Ixazomib Impurity 5 CAS CATO-C4X-12675
| CAS No. | CATO-C4X-12675 |
| Molecular Formula | C14H18Cl2N2O3 |
| Molecular Weight | 333.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 333.21 g/mol gives Ixazomib Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ixazomib Impurity 5 (CAS CATO-C4X-12675), a pharmacopoeial impurity reference standard (molecular formula C14H18Cl2N2O3, MW 333.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H18Cl2N2O3, Ixazomib Impurity 5 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 333.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ixazomib Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18Cl2N2O3 |
| Molecular Weight | 333.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ixazomib Standards
- Ixazomib Impurity 6 (CAS CATO-C4X-12676)
- Ixazomib Impurity 62 (CAS CATO-C4X-126762)
- Ixazomib Impurity 4 (CAS CATO-C4X-12674)
- Ixazomib Impurity 55 (CAS CATO-C4X-126755)
- Ixazomib Impurity 7 (CAS CATO-C4X-12677)
- Ixazomib Impurity 8 (CAS CATO-C4X-12678)
- Ixazomib Impurity 73 (CAS CATO-C4X-126773)
- Ixazomib Impurity 43 (CAS CATO-C4X-126743)
Recommended Standards
- N-(2-(1H-Indol-3-yl)ethyl)-3,4-dichlorobenzamide (CAS 22174-00-1)
- Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]isothiazole-3-carboxylate (CAS 936923-42-1)
- [4-(4-Bromobutoxy)phenyl]-phenylmethanone (CAS 101308-54-7)
- Ethyl 4-(3,3-bis(2-chloroethyl)ureido)benzoate (CAS 92302-31-3)
- Flurbiprofen Impurity 44 (CAS CATO-C4X-144444)
- Safinamide Impurity 23 (CAS CATO-C4X-159023)
- Diltiazem EP Impurity F HCl (CAS 75472-91-2(free base))
- Ethyl 5-amino-1-(3-methoxyphenyl)-1H-pyrazole-3-carboxylate (CAS 1427013-93-1)
- Prilocaine Impurity 13 (CAS 19343-15-8)
- Ethyl 3,4-dibromo-2,5-difluorophenylacetate (CAS 1806350-39-9)
- H-D-Val-Leu-Lys-pNA · 2 HCl (CAS 62354-43-2)
- 8-Boc-3,8-diazabicyclo[4.2.0]octane (CAS 848591-80-0)
- Idarubicin Impurity 6 (CAS CATO-C4X-13746)
- Custom peptides (CAS CATO-CPTD788509)
Why CATO?
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