Ixazomib Impurity 57 CAS CATO-C4X-126757
| CAS No. | CATO-C4X-126757 |
| Molecular Formula | C24H32BCl3N2O4 |
| Molecular Weight | 529.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 529.69 g/mol gives Ixazomib Impurity 57 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Ixazomib Impurity 57 (CAS CATO-C4X-126757, C24H32BCl3N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ixazomib Impurity 57 (C24H32BCl3N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ixazomib Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H32BCl3N2O4 |
| Molecular Weight | 529.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ixazomib Standards
- Ixazomib Impurity 26 (CAS CATO-C4X-126726)
- Ixazomib Impurity 27 (CAS CATO-C4X-126727)
- Ixazomib Impurity 28 (CAS CATO-C4X-126728)
- Ixazomib Impurity 58 (CAS CATO-C4X-126758)
- Ixazomib Impurity 59 (CAS CATO-C4X-126759)
- Ixazomib Impurity 76 (CAS CATO-C4X-126776)
- Ixazomib citrate (CAS 1201902-80-8)
- Ixazomib Citrate (CAS 1239908-20-3)
Recommended Standards
- Glycochenodeoxycholic Acid 3-Sulfate (CAS 67030-54-0)
- Metoclopramide impurity 73 (CAS CATO-C4X-141573)
- (S,R,S)-AHPC-C4-NH2 (CAS 2138439-53-7)
- Raloxifene Impurity 10 (CAS CATO-C4X-174310)
- Betacarotene impurity 10 (CAS CATO-C4X-281510)
- Capecitabine Impurity 42 (CAS CATO-C4X-102442)
- Falecalcitriol impurity 2 (CAS 303015-34-1)
- Norphensuximide-D5 (CAS 3464-18-4)
- 2-Aminoethane-d (CAS 352438-83-6)
- 1-(Oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one (CAS 288862-73-7)
- 4,6-Dimethylisophthalic acid (CAS 2790-09-2)
- 8-Chloro-6-hydroxyquinoline (CAS 18119-24-9)
- 3-Amino-6-ethyl-N-(4-fluorophenyl)-4-(trifluoromethyl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 939893-72-8)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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