Ixazomib Impurity 76 CAS CATO-C4X-126776
| CAS No. | CATO-C4X-126776 |
| Molecular Formula | C24H32BCl3N2O4 |
| Molecular Weight | 529.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ixazomib Impurity 76.
As a process- or degradation-related impurity, Ixazomib Impurity 76 (CAS CATO-C4X-126776, C24H32BCl3N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H32BCl3N2O4, Ixazomib Impurity 76 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 529.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ixazomib Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H32BCl3N2O4 |
| Molecular Weight | 529.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ixazomib Standards
- Ixazomib Impurity 26 (CAS CATO-C4X-126726)
- Ixazomib Impurity 27 (CAS CATO-C4X-126727)
- Ixazomib Impurity 28 (CAS CATO-C4X-126728)
- Ixazomib Impurity 57 (CAS CATO-C4X-126757)
- Ixazomib Impurity 58 (CAS CATO-C4X-126758)
- Ixazomib Impurity 59 (CAS CATO-C4X-126759)
- Ixazomib citrate (CAS 1201902-80-8)
- Ixazomib Citrate (CAS 1239908-20-3)
Recommended Standards
- Metoclopramide impurity 73 (CAS CATO-C4X-141573)
- Raloxifene Impurity 10 (CAS CATO-C4X-174310)
- Fexofenadine Impurity 25 (CAS 174483-06-8)
- UNC1215 (CAS 1415800-43-9)
- Terbutaline Impurity 34 (CAS 28924-18-7)
- Apixaban Impurity 89 (CAS CATO-C4X-108889)
- Atenolol Impurity 26 (CAS CATO-C4X-154926)
- (1R,3r)-3-((tert-butoxycarbonyl)amino)cyclobutyl methanesulfonate (CAS 871014-17-4)
- U0124 (CAS 108923-79-1)
- 1-[(3-hydroxyphenyl)methyl]piperidin-4-ol (CAS 90287-66-4)
- methyl 2-oxopiperidine-4-carboxylate (CAS 25504-47-6)
- 2-(Furan-2-yl)-2-(thiophen-2-ylsulfonyl)ethan-1-amine (CAS 903094-88-2)
- 1,3-Diiodo-5-nitrobenzene (CAS 57830-60-1)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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